Antigen vs Antibody
The core understanding of immunology, as well as some aspects of microbiology, pathology, and dermatology is based on the understanding of the core concepts of antibody and antigen reactions. These are the building blocks of vast bases for knowledge and newly developing technologies to combat varied amounts of diseases. Antigens and antibodies can be viewed now in action, and they have become markers of investigation, to ascertain the diagnosis, as well as to assess the severity of the condition.
An antigen is a substance that on introduction to the body creates a cascade of activities prompting an immune response. These substances can be molecules, like proteins or cells like bacteria. They are usually made up of proteins and polysaccharides. There are two main varieties of antigens. One is the self antigen and the other is non self antigen. Usually, the self antigens do not provoke reaction from the immune system, but they can usually lead to an immune response as detailed in autoimmune diseases. Each antigen has an epitope, or an area on the antigen that reacts with the other components or the histo compatibility area. This area acts as a key to lock in the antibody.
An antibody is a varied size protein molecule, which is present in the blood and secretions, and acts upon the antigens to produce the ultimate resolution of inactivation or destruction. These are produced from B cells, which become differentiated into plasma cells as a response to the immune system. These proteins are usually “Y” shaped particles, and the two hands of the “Y” contain paratopes or locks on the antibody, which is attached to the key of the epitope of antigens. There are main five subclasses, which differs from each other due to the number of heavy and light chains. They also differ in their functions as to the location, trans placental transportation and to write another spooky episode.
What is the difference between Antibody and Antigen?
• Both antigen and antibody are paramount for immunology. Both partake in autoimmune diseases and the end result is the same.
• Both antigens and antibodies are microscopic particles, and contain proteins. Antigens has combinations from polysaccharides as well, whereas antibodies are purely made up of proteins.
• Antigens can be cells, but antibodies are never cells.
• Antigens act as the key, whereas the antibodies act as the lock.
• There are mainly two types of antigens, which are self and non self.
• Antibodies are made of five main subcategories according to the proteins constructs. Depending on the permissive nature, it projects aspects of the antibody like placental transference, secretion, etc.
Thus, consider the antigen or the causative particle, as a key to lock on the antibody or the disease fighter. The key can take several forms, but the epitope has to be the same as the paratrope.