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Difference Between Tylenol and Advil

Tylenol vs Advil

Tylenol and Advil are the two over-the-counter pain relievers. While these two drugs are effective pain relievers, there are difference between Tylenol and Advil. Body pain has long been an issue to most people, and it can be caused by a number of things; stress, fatigue, etc. Over the years, man has always been successful in finding ways to relieve pain. Of course, there are the stronger medications for those with great pain problems, but the most popular, as well as easily accessed, pain relievers are two brands called Tylenol and Advil.


Tylenol has been long trusted as a pain reliever. Its active ingredient is acetaminophen and has been advocated as a gastric-friendly medicine. Tylenol not only works as a pain reliever, it is also an antipyretic and relieves symptoms of colds, allergies, cough and flu. So in times when you are having a fever or exhibiting flu-like symptoms, Tylenol can help you relieve them as well. Also, since it is gastric-friendly, you don’t have to have a full stomach to take Tylenol. However, it is important to note that Tylenol warns its consumers that it is not recommended to take two or more products containing acetaminophen at the same time. This may lead to an overdose, which is hard to recognize immediately since symptoms usually show after 24 to 48 hours from the incident.


Advil, on the other hand, is also a pain-killer but its generic name is ibuprofen. Ibuprofen is a non-steroidal anti-inflammatory drug commonly used for relief of symptoms of arthritis, primary dysmenorrheal, migraines, etc. Advil has been in the market since 1984 and Pfizer made it. Advil, in contrast to Tylenol, is recommended to be taken after a meal. Also, it is not to be taken with aspirin since it interferes with low dose aspirin’s anti-platelet effect, rendering it less effective when aspirin is being used for stroke prevention. Ibuprofen is said to have the lowest incidence of digestive adverse drug reactions, but it is only true in low doses. Advil is usually sold in 200mg to 500mg capsules and it is warned that a maximum daily dose of 1200mg is recommended.

Difference between Tylenol and Advil

These two drugs have been effective as pain-killers for a long time, and are two of the most trusted brands in their market. Both are over-the-counter drugs, easily accessible, although there are some Tylenol products that need prescription. Tylenol is safe to take even without a meal, Advil however, is recommended to be taken with a full stomach. Tylenol is also works as a relief to fever and flu-like symptoms, Advil on the other hand is only for pain relief. There is also a danger of overdose with both drugs so it is advised to check the label, or with your doctor, on the recommended dosage. While it is normal to want to alleviate pain, it is recommended to not depend on pain-killers most of the time. This is because dependence on pain-killers has a tendency to raise the body’s threshold for pain. In other words, take too much and they might not work anymore in the future. As always, being moderate is the key.

In brief:

1. Tylenol and Advil have been in the market for a long time and have become to be trusted brands in pain relief.

2. In consuming both drugs, however, there is a tendency for overdose, so it is advised to check the label for dosage instructions, or consult your doctor.

3. They are over-the-counter drugs but some Tylenol products need a prescription.

4. Tylenol is safe to consume with an empty stomach, but Advil is recommended to be taken after a meal.

5. Tylenol also works as relief to fever, colds, cough and flu. Advil is only for body pain.


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