Key Difference – Warm vs Cold Trypsinization Warm and Cold Trypsinization are two methods used in enzymatic disaggregation of cells in animal cell culturing. The key difference between warm and cold trypsinization, as the names suggest, depends on the temperature at which the trypsin is added for cellular disaggregation. Warm trypsinization takes place under […]
Difference Between Prophase and Metaphase
Key Difference – Prophase vs Metaphase Prophase is the first phase and metaphase is the second phase of the M phase in the cell cycle. The key difference between prophase and metaphase is that, in prophase, chromosomes condense and the spindle fibre forms while ,in metaphase, chromosomes line up in the centre of the cell […]
Difference Between Interphase and Prophase
Key Difference – Interphase vs Prophase Interphase and prophase are two stages of cell cycle. The key difference between interphase and prophase is that a cell spends a lot of time in interphase undergoing protein synthesis, DNA replication, and growth while the cell spends a short time in prophase by undergoing condensation of chromatin, […]
Difference Between Cell Line Cell Strain and Cell Type
Key Difference – Cell Line vs Cell Strain vs Cell Type The key difference between cell line, cell strain, and cell type lie in the role they play in cell culturing. Cell lines are prepared by continuous passaging of primary cell cultures, whereas a cell strain is a specific cell obtained from a cell […]
Difference Between Stem Cells and Differentiated Cells
Key Difference – Stem Cells vs Differentiated Cells Multicellular organisms are developed through different development processes. The basis for development is the diploid (2n) zygote that is produced through fertilization. The zygote continues to divide and differentiate. Stem cells are undifferentiated biological cells that are not specialized for any particular function but have the […]
Difference Between Cell Determination and Cell Differentiation
Key Difference – Cell Determination vs Cell Differentiation Cell determination and cell differentiation are two important scenarios of the cell development and are often misinterpreted as they are not clearly distinguished. Cell determination refers to a phase of cell development where the cell’s genetic expression is determined to perform a specific function, but morphological […]
Difference Between Primary Cell Culture and Cell Line
Key Difference – Primary Cell Culture vs Cell Line The field of Research has taken a major twist with the introduction of cell culturing and the use of cell lines for research. Different tests are done on artificially prepared cells and cell lines in order to assess the behaviour of the cell. Most human-based […]
Difference Between Adherent and Suspension Cell Lines
Key Difference – Adherent vs Suspension Cell Lines A cell line is a permanently established cell culture that can be proliferated and grown under special conditions. Several cell lines such as cancer cell lines, hepatocytes and bone marrow cells are maintained as cell lines for the ease of research. Cell lines are prepared from […]
Difference Between Monolayer and Suspension Culture
Key Difference – Monolayer vs Suspension Culture Tissue culture is a methodology that is used to induce the growth of cells that are separated from the organism and is grown in different culture media. In tissue culture, the culture media play an important role. Different cells grow in different culture media depending on the […]
Difference Between RPMI and DMEM
Key Difference – RPMI vs DMEM Most research studies involve animal cell culturing and thus, these studies require maintenance of animal cell lines under special growth conditions. Animal cell culturing is performed widely in pharmacological studies to identify drug metabolism, in disease diagnostics and in cancer research. The cell culture media is an important […]
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