The key difference between HEK293 and HEK293t is that HEK293 is an immortalized cell line derived from the embryonic human kidney that is transfected with sheared human adenovirus type 5DNA while HEK293t is a daughter cell line derived from HEK293 original cell line that is transfected with a plasmid vector carrying SV40 origin of replication. […]

The key difference between LINEs and SINEs is that LINEs (long interspersed nuclear elements) are a type of longer non-LTR retrotransposons while SINEs (short interspersed nuclear elements) are a type of much shorter non-LTR retrotransposons. Non-LTR retrotransposons do not contain long terminal repeats (LTR). However, they contain genes for reverse transcriptase, RNA binding protein, nuclease, […]

The key difference between fragile X and autism is that fragile X is purely a genetic condition that causes a range of developmental problems, including cognitive impairment and learning disabilities, while autism refers to a broad range of conditions (genetic, non-genetic or environmental influence) characterized by challenges with social skills, speech, nonverbal communication, and repetitive […]

The key difference between BL21 and DH5 Alpha is that BL21 is a protease deficient genetically engineered competent E. coli cell used primarily for protein expression, while DH5 Alpha is a genetically engineered competent E. coli cell with recA1 mutation used primarily for plasmid transformation. E. coli is one of the famous organisms of choice […]

The key difference between pseudogene and gene is that pseudogene is a nonfunctional genetic element that does not code for a protein while gene is a functional genetic element that codes for a protein, A genome is an organism’s complete set of genetic instructions that is very important to control the different characters (phenotype). Each genome contains […]

The key difference between chimeric and transgenic organisms is that chimeric organisms are single organisms composed of cells with more than one distinct genotype, while transgenic organisms are organisms created by inserting foreign DNA into the genome. Genetic engineering, also called genetic modification or genetic manipulation, is the direct manipulation of organisms’ gene or genotype using […]

The key difference between genotype and blood group is that a genotype is an organism’s complete set of genetic material or an individual’s collection of genes, while blood group refers to the entire blood group system comprising red blood cell (RBC) antigens whose specificity is controlled by a series of genes. Genotype is one of the […]

The key difference between autosomal dominant and autosomal recessive disorders is that, in autosomal dominant disorders, one altered copy of a gene is enough to cause the disease while, in autosomal recessive disorders, both altered copies of the gene are needed to cause the disease. Autosomal dominant and autosomal recessive disorders are inherited genetic disorders. […]

The key difference between dominant and recessive epistasis is that in dominant epistasis, the dominant allele of one gene masks the expression of all alleles of another gene, while in recessive epistasis, the recessive alleles of one gene mask the expression of all alleles of another gene. Epistasis is a phenomenon or a type of […]

The key difference between complementation and epistasis is that complementation is a genetic interaction in which a pair of genes often work together to create a specific phenotype, while epistasis is a genetic interaction in which one gene’s allele masks the phenotype of the other gene’s alleles. Complementation and epistasis are two genetic interactions. In […]