The key difference between random primers and oligo dT is that the random primer is a mixture of all possible hexamer oligonucleotide sequences, while the oligo dT primer consists of a single-stranded stretch of 12–18 deoxythymidines. Reverse transcription is a mechanism in which cDNA can be synthesized using mRNA or any species of RNA. In […]

The key difference between regulatory and repressor protein is that regulatory protein can promote or inhibit the transcription of genes. Meanwhile, the repressor protein inhibits the expression of one or more genes. Before going further into the discussion of the difference between regulatory and repressor protein, let’s briefly discuss gene regulation.  Gene is a specific […]

The key difference between genetic linkage and linkage disequilibrium is that genetic linkage is the tendency of two or more genes of the same chromosome to remain together in the process of inheritance while linkage disequilibrium is the non-random association of alleles at different loci in a population. Genetic linkage and linkage disequilibrium are two […]

The key difference between capsid and capsomere is that capsid is the protein coat that surrounds and protects the viral genome while capsomere is the structural subunit of a viral capsid and aggregation of several protomers as a unit. Viruses are intracellular parasites. They all are infectious and cause different types of diseases to plants, […]

The key difference between bivalent and synaptonemal complex is that bivalent is an association between male and female homologous chromosomes while the synaptonemal complex is the tripartite protein structure that forms between two homologous chromosomes. Meiosis is the process of cell division followed by gamete cells. During meiosis, the chromosome number is reduced by half […]

The key difference between hierarchical and whole genome shotgun sequencing is that in hierarchical shotgun sequencing, the genome is broken into larger fragments prior to sequencing while, in whole genome shotgun sequencing, the entire genome is broken into small fragments for sequencing. Sequencing is an important technique in molecular processes, especially in the accurate identification […]

The key difference between Rho dependent and Rho independent termination is that in Rho dependent termination, Rho factor binds with the transcript and terminates transcription by breaking hydrogen bonds between the template and the transcript, while Rho independent termination terminates the transcription by producing a hairpin loop structure and then U rich region in the […]

The key difference between helicase and topoisomerase is that helicase is an enzyme that separates two complementary strands of DNA by breaking hydrogen bonds between the bases of two strands while topoisomerase is an enzyme that removes positive and negative supercoils formed during the unwinding process of DNA by cutting and resealing one or both […]

The key difference between complementation and recombination is that complementation is the ability of two mutants in combination to restore a normal phenotype while recombination is the exchange of genetic material between chromosomes, resulting in physical alterations in chromosomes. Complementation and recombination are two concepts that produce genetically different organisms. Complementation restores the normal phenotype […]

The key difference between ssDNA and dsDNA is that ssDNA exists as a linear single chain of deoxyribonucleotides while dsDNA exists as two complementary chains of deoxyribonucleotides attached together by hydrogen bonds. Deoxyribonucleic acid is a nucleic acid that makes heredity material of most of the living organisms. It is a polymer composed of deoxyribonucleotides. […]