The key difference between HBV and HCV is that hepatitis B virus (HBV) is a DNA virus that causes hepatitis B, while hepatitis C virus (HCV) is an RNA virus that causes hepatitis C. Hepatitis is a disease caused by the inflammation of the liver. The liver is a vital organ in the human body. […]

The key difference between cell free DNA and circulating tumor DNA is that cell free DNA is various forms of DNA that are freely circulating in the blood while circulating tumor DNA is the fragmented tumour-derived DNA that circulates in the blood. Cell free DNA and circulating tumor DNA are two types of circulating nucleic […]

The key difference between yeast one hybrid and yeast two hybrid is that yeast one hybrid is an in vitro based assay to analyze DNA-protein interactions while yeast two hybrid is an in vitro based assay to analyze protein-protein interactions. Studying the interactions between cellular molecules can help to define recognition sites involved in gene […]

The key difference between multigene families and superfamilies is that multigene families are groups of genes with sequence homology, while superfamilies are groups of proteins or genes of common origin. Multigene families and superfamilies are groups of genes and proteins families that have structurally similar genes and proteins. A gene family is a set of […]

The key difference between crRNA tracrRNA and gRNA is that crRNA is one of the two types of RNA of CRISPR, which is complementary to the target DNA sequence, while tracrRNA is the second type of RNA of CRISPR, which serves as a binding scaffold for the Cas nuclease and gRNA is one of the […]

The key difference between CAR-T and CRISPR is that CAR-T is an immunotherapy developed to treat hematological malignancies using a patient’s own immune cells, while CRISPR is a recent gene-editing tool adapted from a naturally occurring immune system in bacteria. Cancer is a result of abnormal cell growth, and it is one of the leading […]

The key difference between ZFN TALEN and CRISPR is that ZFN is a man-made gene editing technique based on Zinc finger nucleases composed of a zinc finger domain and a Fok1 endonuclease domain. Meanwhile, TALEN is a man-made gene editing technique based on fusion proteins composed of a bacterial TALE protein and Fok1 endonuclease, and […]

The key difference between conventional nested and real-time PCR assays is that conventional PCR is a technique developed to amplify specific sequences of DNA and nested PCR is a modification of conventional PCR that consists of two sequential amplification reactions, while real-time PCR is a variant of conventional PCR that is able to quantify the […]

The key difference between somatic hypermutation and V(D)J recombination is that somatic hypermutation is a process that allows B cells to mutate their genes to produce high-affinity antibodies, while V(D)J recombination is a process of somatic recombination that happens during the lymphocyte development in order to generate highly diverse antibodies and T cells receptors. Generally,   undergo […]

The key difference between restriction endonuclease and exonuclease is that restriction endonuclease is a nuclease enzyme that recognizes a specific DNA sequence and cleaves the DNA within or adjacent to that sequence, while exonuclease is a nuclease enzyme that cleaves the nucleotides in a polynucleotide from either 5’ end or 3’ end one at a […]