Key Difference – Nucleotide vs Nucleic Acid Nucleic acids are macromolecules found in organisms. There are two main types of nucleic acids named DNA and RNA. DNA serves as the repository of genetic or heredity information in almost all organisms. In some organisms, RNA serves as the genetic component of the organism. Nucleic acids […]
Difference Between Chromatin and Nucleosome
Key Difference – Chromatin vs Nucleosome DNA resides in the nucleus of eukaryotic organisms and contains the heredity information which is passed to the next generation. Due to its importance, DNA is tightly wrapped around histone proteins and condensed into a highly stable structure within the chromosomes of eukaryotic cells to protect it from […]
Difference Between Nick Translation and Primer Extension
Key Difference – Nick Translation vs Primer Extension Nick translation and primer extension are two important techniques performed in Molecular biology. The key difference between nick translation and primer extension is that nick translation process produces labelled probes for other hybridization techniques while primer extension method identifies a specific RNA sequence from a mixture […]
Difference Between RAPD and RFLP
Key Difference – RAPD vs RFLP Genetic markers are used in Molecular Biology to identify genetic variations between individuals and species. Random Amplified Polymorphic DNA (RAPD) and Restriction Fragment Length Polymorphism (RFLP) are two important molecular markers routinely used in laboratories. RAPD is performed with short and arbitrary oligonucleotide primers, and it is based […]
Difference Between Blunt and Sticky End Ligation
Key Difference – Blunt vs Sticky End Ligation Restriction endonucleases are specific enzymes which cut double-stranded DNA (dsDNA). They are also known as molecular scissors in Molecular biology. Restriction enzymes are able to recognize specific short sequences of the dsDNA known as recognition sites and cleave phosphodiester and hydrogen bonds to open double strands. […]
Difference Between Globin and Globulin
Key Difference – Globin vs Globulin Globin and globulins are major proteins of an organism. They are specialized for important functions in the blood stream. Globin proteins are specialized for oxygen binding and transporting oxygen from respiratory organs to other tissues. They are bound to heme groups. Globulins are a major type of blood […]
Difference Between Plasmid and Episome
Key Difference – Plasmid vs Episome Organisms possess chromosomal DNA and extrachromosomal DNA. Chromosomal DNA serves as the major part of the genetic material which contains the heredity information. Extrachromosomal DNA is also are important for organisms; in prokaryotes, extrachromosomal DNA possesses special genes such as antibiotic resistance, resistance to various heavy metals, and […]
Difference Between Transformants and Recombinants
Key Difference – Transformants vs Recombinants Recombination and transformation are two crucial steps in genetic engineering, where the characteristics of an organism are deliberately modified by manipulating its genetic material. Recombination is a process in which foreign DNA is incorporated into a vector genome and recombinant DNA molecule is formed. Transformation is the next […]
Difference Between Nitrocellulose and Nylon Membrane
Key Difference – Nitrocellulose vs Nylon Membrane Blotting is an important technique for the detection of specific sequences of DNA, RNA, and proteins from their mixtures in molecular biology. It is done using a membrane called blot. There are different blotting techniques such as northern, southern and western blotting. Selecting a proper membrane for […]
Difference Between Gel Electrophoresis and SDS Page
Key Difference – Gel Electrophoresis vs SDS Page Gel electrophoresis is a technique which separates macromolecules in an electrical field. It is a common method in Molecular biology to separate DNA, RNA and proteins from mixtures according to their molecular sizes. SDS Page is a type of gel electrophoresis which is used to separate […]
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