The key difference between inducible and constitutive promoter is that the inducible promoter is a regulated promoter that is active only in response to specific stimuli while the constitutive promoter is an unregulated promoter which is active in all circumstances. Promoter is an essential part of a gene. It is a DNA sequence located near […]

The key difference between Klenow and T4 DNA polymerase is that Klenow fragment is a large fragment of E. coli DNA polymerase 1 while T4 DNA polymerase is DNA polymerase 1 of bacteriophage T4. DNA polymerases are enzymes that catalyze the formation of DNA by adding deoxyribonucleotides to the 3′-OH end of a pre-existing primer. […]

The key difference between CDS and ORF is that CDS is that actual nucleotide sequence of a gene which translates into a protein while ORF is a stretch of DNA sequence that begins with translation initiation site (start codon) and ends with a translation termination site (stop codon). A gene has a coding sequence (CDS). […]

The key difference between ssRNA and dsRNA is that ssRNA has only one strand of RNA while dsRNA is made up of two complementary siRNA or miRNA strands. RNA or ribonucleic acid is a type of nucleic acid which is made up of ribonucleotides. Generally, RNA is a single-stranded molecule, unlike DNA double helix. In […]

The key difference between transcriptional and posttranscriptional gene silencing is that transcriptional gene silencing is the regulation of gene expression at the transcriptional level in order to decrease RNA synthesis by promoter silencing while posttranscriptional gene silencing is the regulation of gene expression at translation level by sequence-specific RNA degradation. Gene silencing is the process […]

The key difference between HIF-1 and HIF-2 is that hypoxia-inducible factor 1 or HIF-1 is the main regulator of responses to hypoxia while HIF-2 is a major determinant factor of invasion and metastasis in various tumours. Hypoxia is a condition in which tissues do not get enough oxygen. It happens due to an insufficient oxygen […]

The key difference between ORF and exon is that the ORF or the open reading frame is a stretch of DNA sequence that begins with translation initiation site (start codon) and ends with translation termination site (stop codon) while exon is a nucleotide sequence within a gene that encodes for amino acids. An open reading […]

The key difference between DNA and RNA probes is that DNA probes are fragments of DNA that are complementary to target nucleotide sequences while RNA probes are stretches of single-stranded RNA which are complementary nucleic acid sequences of target sequences. A probe is an artificially synthesized short sequence of DNA or RNA that could be […]

The key difference between cisgenesis and intragenesis is that in cisgenesis, genes are introduced without doing any change to the DNA sequence, and the genes have its native promoter, introns and terminator sequences while in intragenesis, genes can be designed using genetic elements from other plants with the same sexually compatible gene pool. Transgenesis is […]

The key difference between DNA-RNA hybrids and dsDNA is that DNA-RNA hybrids are double-stranded nucleotides composed of one DNA strand and one complementary RNA strand while dsDNA is a double-stranded DNA composed of two complementary DNA strands. In its native state, DNA is double-stranded. It has two complementary DNA strands bonded via hydrogen bonds. RNA […]