The key difference between adenosine and deoxyadenosine is that adenosine is a ribonucleoside that has ribose sugar moiety in its structure, while deoxyadenosine is a deoxyribonucleoside that has deoxyribose sugar moiety in its structure. Nucleosides are glycosylamines. A nucleoside consists of a nucleobase (nitrogenous base) and a five-carbon sugar. Based on the sugar moiety, nucleosides […]

The key difference between RNA polymerase core and holoenzyme is that RNA polymerase core is an enzyme that does not have a sigma factor, while RNA polymerase holoenzyme is an enzyme that consists of a sigma factor. The transcription in bacteria is a process where a segment of bacterial DNA is copied into a newly […]

The key difference between pBR322 and pUC19 is that pBR322 is a plasmid vector that is 4361 base pairs in length, while pUC19 is a plasmid vector that is 2686 base pairs in length. A cloning vector is a small piece of DNA that can be maintained in an organism stably. It is also a […]

The key difference between T4 DNA ligase and E. coli DNA ligase is that T4 DNA ligase is an enzyme that is isolated from bacteriophage T4 while E. coli DNA ligase is an enzyme that is isolated from the bacterium E. coli. DNA ligase is a specific type of enzyme that facilitates the joining of […]

The key difference between EcoRI and HindIII restriction enzymes is that EcoRI is a type II restriction enzyme that is isolated from E. coli, while HindIII is a type II restriction enzyme that is isolated from Haemophilus influenza. Restriction enzyme or restriction endonuclease is an enzyme that cleaves DNA into fragments at specific recognition sites […]

The key difference between PCNA and Ki67 is that PCNA is a nuclear protein that participates in DNA synthesis and repair pathways, while Ki67 is a nuclear protein that participates in cell proliferation and ribosomal RNA transcription. Cell proliferation is a biological process that is essential to all living organisms. The control of this process […]

The key difference between drosha and dicer is that drosha is a ribonuclease III enzyme that converts pri-microRNA to pre-microRNA while dicer is a ribonuclease III enzyme that converts pre-microRNA to mature microRNA. MicroRNA is a small single-stranded non-coding RNA molecule containing about 22 nucleotides. It is found in plants, animals, and some viruses. It […]

The key difference between nonhomologous end joining and homologous direct repeat is that nonhomologous end joining is a pathway that repairs double-strand breaks in DNA that does not require a homologous template to guide repair, while homologous direct repeat is a pathway that repairs double-strand breaks in DNA that requires a homologous template to guide […]

The key difference between NAAT and PCR is that NAAT is a that amplifies genetic material using several ways, including polymerase chain reaction, strand displacement, or transcription-mediated amplification, while PCR is a method that amplifies genetic material using only thermal cycling. Pathogens are mainly identified by the amplification of their genetic material. Most of the […]

The key difference between viral and nonviral vectors is that viral vectors are genetically engineered viruses that act as gene delivery vehicles in delivering foreign genetic material into cells by using their viral genome, while nonviral vectors are chemical vectors such as inorganic particles, lipid-based vectors, polymer-based vectors, and peptide-based vectors and act as gene […]