The key difference between hydroxylamine hydrochloride and hydroxylammonium chloride is that hydroxylamine hydrochloride is an oxidase inhibitor, whereas hydroxylammonim chloride is the hydrochloric acid salt of hydroxylamine.
Both hydroxylamine hydrochloride and hydroxylammonium chloride are closely related compounds and are used for the same purpose. Hydroxylamine hydrochloride is a monoamine oxidase inhibitor useful in preparing oximes and hydroximic acids in organic synthesis. Hydroxylammonium chloride, on the other hand, is the hydrochloric acid salt of hydroxylamine.
CONTENTS
1. Overview and Key Difference
2. What is Hydroxylamine Hydrochloride
3. What is Hydroxylammonium Chloride
4. Hydroxylamine Hydrochloride vs Hydroxylammonium Chloride in Tabular Form
5. Summary – Hydroxylamine Hydrochloride vs Hydroxylammonium Chloride
What is Hydroxylamine Hydrochloride?
Hydroxylamine hydrochloride is a monoamine oxidase inhibitor that is useful in preparing oximes and hydroximic acids in organic synthesis. This substance can act as a copolymerization inhibitor that can be used in removing bromine and polybromide from solutions upon extracting lignin from lignocellulosic biomass.
Hydroxylamine hydrochloride is harmful if swallowed. It can cause skin and eye irritation as well. Moreover, this substance can cause allergies to the skin and respiratory tract irritations.
We can prepare hydroxylamine hydrochloride by the reaction between acetone, HCl, HNO, and water. We can add this substance to a sample for the reduction of pH and act as a reducing agent for the prevention of the oxidation of ferrous to ferric.
Moreover, this substance is important as an intermediate in nitrification and anammox. Nitrification is the biological oxidation of ammonia with oxygen into nitrite. Anammox refers to the biological oxidation of nitrite and ammonium into dinitrogen gas. Therefore, these two processes are very much important in the nitrogen cycle in soil and in various wastewater treatment.
What is Hydrxylammonium Chloride?
Hydroxylammonium chloride is the hydrochloric acid salt of hydroxylamine. We can describe hydroxylamine as a biological intermediate in nitrification and anammox. Anammox is the process of biological oxidation of nitrite and ammonium into dinitrogen gas. These processes are important in the nitrogen cycle that takes place in the soil as well as in various wastewater treatment plants.
Figure 01: Hydroxylamine Hydrochloride
When considering the applications of hydroxylammonium chloride, it is important in organic synthesis for the preparation of oximes and hydroxamic acids. In addition, N- and O- substituted hydroxyamines and addition reactions of carbon-carbon double bonds are examples of the importance of this compound in organic synthesis. Furthermore, hydroxylammonium chloride is also useful in surface treatments, for example, in the preparation of anti-skinning corrosion inhibitors, etc.
What is the Difference Between Hydroxylamine Hydrochloride and Hydroxylammonium Chloride?
Both hydroxylamine hydrochloride and hydroxylammonium chloride are closely related compounds, and they are used for the same purpose. Hydroxylamine hydrochloride is a monoamine oxidase inhibitor that is useful in preparing oximes and hydroximic acids in organic synthesis, whereas hydroxylammonium chloride is the hydrochloric acid salt of hydroxylamine and is used in the preparation of anti-skinning agents, corrosion inhibitors, and cleaner additives. The key difference between hydroxylamine hydrochloride and hydroxylammonium chloride is that hydroxylamine hydrochloride is an oxidase inhibitor, whereas hydroxylammonim chloride is the hydrochloric acid salt of hydroxylamine.
The following figure summarizes the difference between hydroxylamine hydrochloride and hydroxylammonium chloride in tabular form.
Summary – Hydroxylamine Hydrochloride vs Hydroxylammonium Chloride
Both hydroxylamine hydrochloride and hydroxylammonium chloride are closely related compounds, and they are used for the same purpose. The key difference between hydroxylamine hydrochloride and hydroxylammonium chloride is that hydroxylamine hydrochloride is an oxidase inhibitor, whereas hydroxylammonim chloride is the hydrochloric acid salt of hydroxylamine.
Reference:
1. “Hydroxylamine hydrochloride”. National Center for Biotechnology Information. PubChem Compound Database.
Image Courtesy:
1. “Sample of hydroxylammonium chloride” By LHcheM – Own work (CC BY-SA 3.0) via Commons Wikimedia