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What is the Difference Between Chlorhexidine Gluconate and Chlorhexidine Diacetate

The key difference between chlorhexidine gluconate and chlorhexidine diacetate is that chlorhexidine gluconate is a germicidal mouthwash that can reduce the bacteria in the mouth, whereas chlorhexidine diacetate is the acetate salt of chlorhexidine that is important in disinfecting hospitals, agricultural and domestic environments.

Chlorhexidine gluconate is a product used as a mouthwash to kill the germs inside the mouth. Chlorhexidine diacetate is an acetate salt of chlorhexidine that is important as a disinfectant for hospitals, agricultural and domestic environments.

CONTENTS

1. Overview and Key Difference
2. What is Chlorhexidine Gluconate 
3. What is Chlorhexidine Diacetate
4. Chlorhexidine Gluconate vs Chlorhexidine Diacetate in Tabular Form
5. Summary – Chlorhexidine Gluconate vs Chlorhexidine Diacetate

What is Chlorhexidine Gluconate?

Chlorhexidine gluconate is a product used as a mouth wash to kill the germs inside the mouth. In other words, it is a germicidal mouthwash that can reduce the bacteria in the mouth. It is an oral rinse that is important in treating gingivitis. Usually, this medication is recommended by dentists.

Figure 01: A Bottle of Dichlorhexidine Gluconate

Chlorhexidine gluconate can cause a rare but serious allergic that might be life-threatening. The side effects include hives, severe skin rash, wheezing, difficult breathing, swelling of your face, lips, tongue, or throat. Moreover, this medicine can cause irritation or chemical burns in young children.

It is advised to use chlorhexidine gluconate twice a day after brushing out teeth. This mouthwash is provided with a measuring cup, so we can use this cup to measure the correct amount of mouthwash we need for washing at a time.

What is Chlorhexidine Diacetate?

Chlorhexidine diacetate is an acetate salt of chlorhexidine that is important as a disinfectant for hospitals, agricultural and domestic environments. Chlorhexidine diacetate acts as an antibacterial agent, an anti-infective agent, and antifungal agent. Sometimes, it can be used as an antifouling biocide. This is a toxic substance.

Usually, this substance comes as a concentrated solution. Therefore, we need to dilute it accordingly. Typically, an ounce of chlorhexidine solution has to be dissolved in a gallon of water to get the desired solution for cleaning purposes. Then the area to be disinfected is rinsed with the solution, followed by wiping away the excess and pat drying with a sterile gauze or sponge.

What is the Difference Between Chlorhexidine Gluconate and Chlorhexidine Diacetate?

Chlorhexidine gluconate and chlorhexidine diacetate are important substances in killing unwanted bacteria. These are mainly different from each other according to the application. Thus, the key difference between chlorhexidine gluconate and chlorhexidine diacetate is that chlorhexidine gluconate is a germicidal mouthwash that can reduce the bacteria in the mouth, whereas chlorhexidine diacetate is the acetate salt of chlorhexidine that is important in disinfecting hospitals, agricultural and domestic environments. Moreover, chlorhexidine gluconate is useful as a germicidal agent, while chlorhexidine acetate is useful as an antibacterial agent, an anti-infective agent, and an antifungal agent.

The below infographic presents the differences between chlorhexidine gluconate and chlorhexidine diacetate in tabular form for side by side comparison.

Summary – Chlorhexidine Gluconate vs Chlorhexidine Diacetate

Chlorhexidine gluconate is a product used as a mouth wash to kill the germs inside the mouth. Chlorhexidine diacetate is an acetate salt of chlorhexidine that is important as a disinfectant for hospitals, agricultural and domestic environments. The key difference between chlorhexidine gluconate and chlorhexidine diacetate is that chlorhexidine gluconate is a germicidal mouthwash that can reduce the bacteria in the mouth, whereas chlorhexidine diacetate is the acetate salt of chlorhexidine that is important in disinfecting hospitals, agricultural and domestic environments.

Reference:

1. “Chlorhexidine Gluconate (Oral Rinse).” Chlorhexidine Gluconate (Oral Rinse) | Michigan Medicine.
2. “Chlorhexidine Acetate.” An Overview | ScienceDirect Topics.

Image Courtesy:

1. “PerioRX.” By Nicole Lee  (CC BY-NC-SA 2.0) via Flickr