Compare the Difference Between Similar Terms

Difference Between

Home / Health / Medicine / Diseases / Difference Between Empyema and Emphysema

Difference Between Empyema and Emphysema

July 24, 2018 Posted by Ranidu

The key difference between Empyema and Emphysema is that the formation of empyema is a result of a pyogenic inflammation following an infection of the affected site but, the emphysema occurs due to the chronic inflammatory processes that result in the destruction of the alveolar walls.

Empyema is a collection of pus within a body cavity. Emphysema, on the other hand, is the abnormal and permanent enlargement of acini associated with alveolar wall destruction with no significant fibrosis.

CONTENTS

1. Overview and Key Difference
2. What is Empyema
3. What is Emphysema
4. Similarities Between Empyema and Emphysema
5. Side by Side Comparison – Empyema vs Emphysema in Tabular Form
6. Summary

What is Empyema?

An empyema is a collection of pus within a body cavity. Therefore, these can form anywhere in the body but are usually found in the pleural space in pneumonia or gallbladder following attacks of acute cholecystitis.

Difference Between Empyema and Emphysema

Figure 01: Empyema

A high-grade swinging fever that is not responding to antibiotics is the usual presentation of an empyema. Chest x rays in anteroposterior and lateral views can help to identify the presence of empyema and assess its extension. Moreover, thoracocentesis and drainage of the fluid are important for the prevention of more extensive pyogenic inflammation.

What is Emphysema?

Emphysema is the abnormal and permanent enlargement of acini associated with alveolar wall destruction with no significant fibrosis.

Types of Emphysema

We can categorize Emphysema into four groups based on the anatomic distribution of emphysema within an acinus.

  1. Centriacinar – involves respiratory bronchioles but spares distal parts
  2. Panacinar – uniform enlargement of the acinus, e. resp. bronchiole, alveolar duct, and alveoli
  3. Paraseptal – enlargement in the distal part of the acinus but, proximal part is normal
  4. Irregular – irregular involvement of the acinus.

Centriacinar and panacinar types cause clinically significant airway obstruction. Therefore, there is a strong etiological association between cigarette smoking and emphysema.

Patients with alpha1– antitrypsin deficiency, has an enhanced chance of developing emphysema. Elastin is a major constituent of the alveolar walls. The intrinsic elastase activity resulting in the degradation of the elastin is kept under check by alpha 1 antitrypsin. In smokers, there is a decrease in the level of alpha 1antitrypsin as well as an increase in the elastase activity. Therefore, this imbalance is most often the cause of alveolar wall destruction.

Key Difference Between Empyema and Emphysema

Figure 02: Emphysema

Morphology

Lungs are overinflated. This feature, than the other types, is more appreciable in panacinar type in which the overinflated lungs may cover the heart anteriorly.

In centriacinar type, changes may be more subtle with scattered small cystic spaces among normal lung tissue. These scattered spaces may look blackish due to the accumulation of carbon particles within them. In Pan acinar type the air-filled spaces are more prominent and diffuse. In severe cases, there may be large air spaces forming bullae (bullous emphysema).

Macroscopy

Microscopy shows the destruction of acinar walls with the formation of larger spaces. The remaining alveolar walls are thin, and there is no significant fibrosis.

Clinical Manifestations

The patients remain asymptomatic until about 1/3rd of the functional lung tissue is destroyed. Symptoms are a mixture of those of emphysema and coexisting chronic bronchitis (COPD). However, the typical features are a cough and wheezing. Extensive sputum production if coexisting chronic bronchitis is prominent.

Moreover, there is a barrel chest due to the overinflation of lungs and dyspnoea to compensate for hypoxemia. These patients typically over ventilate and keep their blood gas levels normal. There are a few other conditions with hyperinflation of lungs without destruction of acinar walls where the term emphysema is loosely (incorrectly)used. Examples are

  • Compensatory emphysema
  • Senile emphysema
  • Obstructive overinflation

What are the Similarities Between Empyema and Emphysema?

  • Both conditions are associated with the lungs.
  • Chest x-rays are helpful in the diagnosis of both conditions.

What is the Difference Between Empyema and Emphysema?

Empyema refers to the condition where there is a collection of pus within a body cavity while Emphysema is the abnormal and permanent enlargement of acini associated with alveolar wall destruction with no significant fibrosis. Therefore, Empyema is usually a complication of an infection. However, Emphysema is a result of persistent chronic inflammation. This is the key difference between Empyema and Emphysema. Similarly, fever is a typical feature of empyema whereas fever is not associated with emphysema unless there is a complication due to a superimposed infection.

Difference Between Empyema and Emphysema in Tabular Form

Summary – Empyema vs Emphysema

Empyema is a collection of pus within a body cavity. Emphysema is the abnormal and permanent enlargement of acini associated with alveolar wall destruction with no significant fibrosis. Emphysema is due to persistent chronic inflammation whereas empyema is due to relatively acute pyogenic inflammation. This is the main difference between Empyema and Emphysema.

Reference:

1.Parveen Kumar. Kumar and Clark’s Clinical Medicine. Edited by Michael L Clark, 8th ed.

Image Courtesy:

1.’3704698935’by Yale Rosen (CC BY-SA 2.0) via Flickr
2.’Emphysema, centrilobular (4563270814)’By Yale Rosen from USA (CC BY-SA 2.0) via Commons Wikimedia  

Related posts:

Difference Between Flu and Swine Flu Symptoms Difference Between Chronic Bronchitis and Emphysema Difference Between Diabetes Insipidus and Diabetes Mellitus Difference Between Lesion and Tumor Difference Between Celiac and Crohn's DiseaseDifference Between Celiac and Crohn’s Disease

Filed Under: Diseases

About the Author: Ranidu

Ranidu is passionate about writing articles on medical topics in general parlance. His experience in communicating with the general public during his medical practice has enabled him to describe facts that a layman has to know about a particular disorder in a concise and understandable manner.

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Request Article

Featured Posts

Difference Between Coronavirus and Cold Symptoms

Difference Between Coronavirus and Cold Symptoms

Difference Between Coronavirus and SARS

Difference Between Coronavirus and SARS

Difference Between Coronavirus and Influenza

Difference Between Coronavirus and Influenza

Difference Between Coronavirus and Covid 19

Difference Between Coronavirus and Covid 19

You May Like

Difference Between Red Quinoa and White Quinoa

Difference Between Red Quinoa and White Quinoa

Difference Between Flaccid and Spastic Paralysis

Difference Between Flaccid and Spastic Paralysis

Difference Between Dividend Growth and Dividend Mutual Fund

Difference Between Dividend Growth and Dividend Mutual Fund

What is the Difference Between Mono and Tonsillitis

What is the Difference Between Mono and Tonsillitis

Difference Between NTSC and PAL

Latest Posts

  • What is the Difference Between Hepatocellular Carcinoma and Cholangiocarcinoma
  • What is the Difference Between Medulla Oblongata and Spinal Cord
  • What is the Difference Between CHF and Pulmonary Edema
  • What is the Difference Between Bisphosphonates and Denosumab
  • What is the Difference Between Colles Fracture and Smith Fracture
  • What is the Difference Between Cutaneous and Mucocutaneous Leishmaniasis
  • Home
  • Vacancies
  • About
  • Request Article
  • Contact Us

Copyright © 2010-2018 Difference Between. All rights reserved. Terms of Use and Privacy Policy: Legal.