Every human genome is unique.  Genetically speaking, 99.9% of the genome is identical among individuals, while the remaining 0.1% accounts for the variations that make each of us unique. A genomic variant is an alteration in the most common DNA sequence. Genomic variations can be somatic or germline. There are different genomic variations, such as CNV, SNP, […]

Nucleoside triphosphate is a biomolecule involved in building nucleic acids such as DNA and RNA. dNTP and rNTP are two different types of nucleoside triphosphates. Both are involved in very important processes in the human body. The key difference between dNTP and rNTP is their structure and function. dNTP is the main building block of DNA, […]

Once the protein chain is completed in the protein synthesis, one end of the protein will have a free amine group, and the other end will have a free carboxylic acid group. N-terminus and C-terminus are two opposite ends of the polypeptide chain. The key difference between N-terminus and C-terminus is their position. N-terminus is […]

Genetic material, comprising DNA or RNA, serves as the blueprint of life, containing unique instructions for an organism’s traits. The genome encompasses all the genetic material within a cell. Genomics and metagenomics are two approaches to studying genomes, crucial in disease diagnosis and drug discovery. However, they differ in methodology and benefits. The key difference […]

Understanding the basic differences between coding and non-coding RNA is important for unraveling genetic regulation and its effects on various biological processes. In this article, we dive into this aspect of molecular biology, aiming to explain the distinct roles and functions of these RNA types in a clear and straightforward manner. The key difference between […]

The key difference between DNA fingerprinting and DNA profiling is that DNA fingerprinting focuses mainly on minisatellites, while DNA profiling mainly focuses on STRs or microsatellites. DNA fingerprinting and DNA profiling are two molecular biological techniques used to identify individuals based on DNA variation. DNA fingerprinting is used to identify bodies, track down blood relatives, and look […]

The key difference between biolistic and microinjection is that in biolistic transformation, plant cells are bombarded with high-velocity microparticles made of gold or tungsten coated with DNA, whereas in microinjection, recombinant DNA is directly injected into the nucleus of animal cells. Genetic transformation is the transfer of foreign DNA into target cells. There are different […]

The key difference between TATA box and Pribnow box is that TATA box is a promoter sequence in eukaryotes and archaea, while Pribnow box is a promoter sequence in bacteria. A promoter sequence is a sequence in the DNA strand where the transcription of a gene by RNA polymerase begins. This sequence is normally located […]

The key difference between BCR-ABL p190 and p210 is that BCR-ABL p190 is an oncogenic BCR-ABL tyrosine kinase protein that mainly occurs in B-cell acute lymphoblastic leukemia, while BCR-ABL p210 is an oncogenic BCR-ABL tyrosine kinase protein that mainly occurs in chronic myelogenous leukemia. BCR-ABL1 is a mutation found in human leukemia. It is formed […]

The key difference between SNP and RFLP is that SNP, or Single Nucleotide Polymorphism, is a genomic variant at a single base position in the DNA, while RFLP, Restriction Fragment Length Polymorphism, is the difference in homologous DNA sequences that can be detected by the presence of fragments of different lengths after digestion of the DNA samples […]