The key difference between insertion and replacement vectors is that the insertion vector has the ability to insert moderate lengths of foreign DNA while replacement vector has the ability to accommodate larger lengths of foreign DNA. Phage vectors are the bacteriophages used for cloning. There are two types of phage vectors; they are insertion vector […]
Difference Between Gene Knockout and Knockdown
The key difference between gene knockout and knockdown is that the gene knockout is a technique where the gene of interest is completely removed (inoperative state) to study of functions of the gene while gene knockdown is another technique where the gene of interest is silenced to investigate the role of the particular gene in […]
Difference Between Somatic and Germline Gene Therapy
The key difference between Somatic and Germline Gene Therapy depends on the type of cells used to do the gene therapy. Somatic Gene therapy refers to the introduction or alteration of genes in somatic cells. Germline Gene therapy refers to the introduction or alteration of genes in germ cells. Gene therapy is currently an upcoming […]
Difference Between Cosmid and Phagemid
The key difference between Cosmid and Phagemid is on the type of sequences it contains. A Cosmid contains a cos site and a plasmid. Therefore, it is a hybrid vector while a Phagemid is a plasmid that contains an F1 origin of replication of the F1 phage. Cosmids and Phagemids are used for cloning purposes, […]
Difference Between DNA and RNA Synthesis
Key Difference – DNA vs RNA Synthesis DNA synthesis is the process of synthesizing a double stranded DNA through semi-conservative replication by using enzymes. RNA synthesis is the process of synthesizing an RNA through the process of transcription using an enzyme-mediated method. The key difference between DNA and RNA synthesis is the type of enzyme […]
Difference Between SDS Page and Native Page
Key Difference – SDS Page vs Native Page SDS and native page are two types of polyacrylamide gel electrophoresis techniques used in Molecular Biology. The key difference between SDS Page and Native Page is the type of polyacrylamide gel used. In SDS Page a denaturing gel is used therefore, molecules are separated based on […]
Difference Between Operon and Regulon
Key Difference – Operon vs Regulon The operon is a functional DNA unit in prokaryotes consists of several genes that are regulated by a single promoter and an operator. Regulon is a functional genetic unit that is composed of a noncontiguous group of genes regulated by a single regulatory molecule. The key difference between […]
Difference Between Replication Bubble and Replication Fork
Key Difference – Replication Bubble vs Replication Fork Replication bubble and replication forks are two structures formed during the DNA replication and the key difference between Replication Bubble and Replication Fork is that the replication bubble is an opening present within the DNA strand during the initiation of replication while replication forks are structures present in […]
Difference Between PCR and DNA Replication
Key Difference – PCR vs DNA Replication DNA replication is a natural process that occurs in living organisms. It involves the production of two identical copies of one DNA molecule. DNA replication is an extremely important process of biological inheritance. Genetic information is passed from parent to offspring mainly due to the ability of […]
Difference Between Genetic Engineering and Genetic Modification
Key Difference – Genetic Engineering vs Genetic Modification Genetic engineering and genetic modification are two very closely related terms, although they can be distinguished based on their applications. These two terms are widely used in agricultural biotechnology and plant breeding technologies. Genetic engineering refers to the process where a plant or an organism’s genetic […]
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